Your Viral Infection History from a Single Drop of Blood : HHMI researchers

AdminAcademics

Elledge                                                                     Image Source: https://www.hhmi.org/

Systematic viral epitope scanning (VirScan). This method allows comprehensive analysis of antiviral antibodies in human sera. VirScan combines DNA microarray synthesis and bacteriophage display to create a uniform, synthetic representation of peptide epitopes comprising the human virome. Immunoprecipitation and high-throughput DNA sequencing reveal the peptides recognized by antibodies in the sample. The color of each cell in the heatmap depicts the relative number of antigenic epitopes detected for a virus (rows) in each sample (columns). Credit: Figure from the print summary of Xu et al., “Comprehensive serological profiling of human populations using a synthetic human virome” SCIENCE, 348:1105 (5 June 2015).

Full Story with Video :

http://www.hhmi.org/news/your-viral-infection-history-single-drop-blood